Recombinant Human SLC26A4 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: SLC26A4-3846H
• Product Overview: SLC26A4 MS Standard C13 and N15-labeled recombinant protein (NP_000432) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Mutations in this gene are associated with Pendred syndrome, the most common form of syndromic deafness, an autosomal-recessive disease. It is highly homologous to the SLC26A3 gene; they have similar genomic structures and this gene is located 3' of the SLC26A3 gene. The encoded protein has homology to sulfate transporters.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 85.5 kDa
• AA Sequence: MAAPGGRSEPPQLPEYSCSYMVSRP VYSELAFQQQHERRLQERKTLRESL AKCCSCSRKRAFGVLKTLVPILEWL PKYRVKEWLLSDVISGVSTGLVATL QGMAYALLAAVPVGYGLYSAFFPIL TYFIFGTSRHISVGPFPVVSLMVGS VVLSMAPDEHFLVSSSNGTVLNTTM IDTAARDTARVLIASALTLLVGIIQ LIFGGLQIGFIVRYLADPLVGGFTT AAAFQVLVSQLKIVLNVSTKNYNGV LSIIYTLVEIFQNIGDTNLADFTAG LLTIVVCMAVKELNDRFRHKIPVPI PIEVIVTIIATAISYGANLEKNYNA GIVKSIPRGFLPPELPPVSLFSEML AASFSIAVVAYAIAVSVGKVYATKY DYTIDGNQEFIAFGISNIFSGFFSC FVATTALSRTAVQESTGGKTQVAGI ISAAIVMIAILALGKLLEPLQKSVL AAVVIANLKGMFMQLCDIPRLWRQN KIDAVIWVFTCIVSIILGLDLGLLA GLIFGLLTVVLRVQFPSWNGLGSIP STDIYKSTKNYKNIEEPQGVKILRF SSPIFYGNVDGFKKCIKSTVGFDAI RVYNKRLKALRKIQKLIKSGQLRAT KNGIISDAVSTNNAFEPDEDIEDLE ELDIPTKEIEIQVDWNSELPVKVNV PKVPIHSLVLDCGAISFLDVVGVRS LRVIVKEFQRIDVNVYFASLQDYVI EKLEQCGFFDDNIRKDTFFLTVHDA ILYLQNQVKSQEGQGSILETITLIQ DCKDTLELIETELTEEELDVQDEAM RTLASTRTRPLEQKLISEEDLAAND ILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: SLC26A4 solute carrier family 26 member 4 [ Homo sapiens (human) ]
• Official Symbol: SLC26A4
• Synonyms: SLC26A4; solute carrier family 26, member 4; DFNB4; pendrin; PDS; sodium-independent chloride/iodide transporter; EVA; TDH2B
• Gene ID: 5172
• mRNA Refseq: NM_000441
• Protein Refseq: NP_000432
• MIM: 605646
• UniProt ID: O43511