Recombinant Human SLC25A27 Protein, His-tagged

• Cat.No.: SLC25A27-544H
• Product Overview: Recombinant Human SLC25A27, transcript variant 1, fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. Transcripts of this gene are only detected in brain tissue and are specifically modulated by various environmental conditions. Alternative splicing results in multiple transcript variants.
• Form: 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
• Molecular Mass: 35.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: SLC25A27 solute carrier family 25, member 27 [ Homo sapiens ]
• Official Symbol: SLC25A27
• Synonyms: SLC25A27; solute carrier family 25, member 27; mitochondrial uncoupling protein 4; FLJ33552; UCP4; UCP 4; uncoupling protein 4; RP11-446F17.2
• Gene ID: 9481
• mRNA Refseq: NM_001204051
• Protein Refseq: NP_001190980
• MIM: 613725
• UniProt ID: O95847