Recombinant Human SLC25A12 protein, His & T7-tagged

• Cat.No.: SLC25A12-1686H
• Product Overview: Recombinant Human SLC25A12 aa. (Thr7~Asp245 (Accession # O75746)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Description: This gene encodes a calcium-binding mitochondrial carrier protein. The encoded protein localizes to the mitochondria and is involved in the exchange of aspartate for glutamate across the inner mitochondrial membrane. Polymorphisms in this gene may be associated with autism, and mutations in this gene may also be a cause of global cerebral hypomyelination. Alternatively spliced transcript variants have been observed for this gene.
• Source: E. coli
• Species: Human
• Tag: His&T7
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 31.1kDa
• Protein length: Thr7~Asp245
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >90%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
• Reconstitution: Reconstitute in sterile ddH2O.
• Isoelectric Point: 5.8

Gene Information

• Gene Name: SLC25A12 solute carrier family 25 member 12 [ Homo sapiens (human) ]
• Official Symbol: SLC25A12
• Synonyms: SLC25A12; solute carrier family 25 member 12; AGC1; ARALAR; EIEE39; calcium-binding mitochondrial carrier protein Aralar1; araceli hiperlarga; calcium binding mitochondrial carrier superfamily member Aralar1; mitochondrial aspartate glutamate carrier 1; solute carrier family 25 (aspartate/glutamate carrier), member 12; solute carrier family 25 (mitochondrial carrier, Aralar), member 12
• Gene ID: 8604
• mRNA Refseq: NM_003705.4
• Protein Refseq: NP_003696.2
• UniProt ID: O75746