Recombinant Human SLC22A4 protein, His & T7-tagged

• Cat.No.: SLC22A4-1212H
• Product Overview: Recombinant Human SLC22A4 aa. (Leu42~Lys141 (Accession # Q9H015) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His&T7
• Protein Length: Leu42~Lys141
• Description: Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is an organic cation transporter and plasma integral membrane protein containing eleven putative transmembrane domains as well as a nucleotide-binding site motif. Transport by this protein is at least partially ATP-dependent.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 15.0kDa.
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 4.9.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: SLC22A4 solute carrier family 22 member 4 [ Homo sapiens (human) ]
• Official Symbol: SLC22A4
• Synonyms: SLC22A4; solute carrier family 22 member 4; OCTN1; DFNB60; solute carrier family 22 member 4; ET transporter; deafness, autosomal recessive 60; ergothioneine transporter; integral membrane transport protein; organic cation/carnitine transporter 1; solute carrier family 22 (organic cation/ergothioneine transporter), member 4; solute carrier family 22 (organic cation/zwitterion transporter), member 4
• Gene ID: 6583
• mRNA Refseq: NM_003059.2
• Protein Refseq: NP_003050.2
• UniProt ID: Q9H015