Recombinant Human SLC10A2 Protein

• Cat.No.: SLC10A2-01H
• Product Overview: Human SLC10A2 full-length ORF (ADR82931.1) recombinant protein without tag.

Specification

• Species: Human
• Source: Wheat Germ
• Description: This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG).
• Form: Liquid
• Molecular Mass: 38.3kDa
• AA Sequence: MNDPNSCVDNATVCSGASCVVPESNFNNILSVVLSTVLTILLALVMFSMGCNVEIKKFLGHIKRPWGICVGFLCQFGIMPLTGFILSVAFDILPLQAVVVLIIGCCPGGTASNILAYWVDGDMDLSVSMTTCSTLLALGMMPLCLLIYTKMWVDSGSIVIPYDNIGTSLVALVVPVSIGMFVNHKWPQKAKIILKIGSIAGAILIVLIAVVGGILYQSAWIIAPKLWIIGTIFPVAGYSLGFLLARIAGLPWYRCRTVAFETGMQNTQLCSTIVQLSFTPEELNVVFTFPLIYSIFQLAFAAIFLGFYVAYKKCHGKNKAEIPESKENGTEPESSFYKANGGFQPDEK
• Applications: Antibody Production
• Usage: Heating may cause protein aggregation. Please do not heat this product before electrophoresis.
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80°C. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 25 mM Tris-HCl of pH8.0 containing 2% glycerol.
• Preparation: in vitro wheat germ expression system with proprietary liposome technology

Gene Information

• Gene Name: SLC10A2 solute carrier family 10 member 2 [ Homo sapiens (human) ]
• Official Symbol: SLC10A2
• Synonyms: ASBT,ISBT,NTCP2
• Gene ID: 6555
• mRNA Refseq: NM_000452.3
• Protein Refseq: NP_000443.2
• UniProt ID: Q12908