Recombinant Human SIGLEC7 Protein, 19-353aa, C-hIgG-His tagged

• Cat.No.: SIGLEC7-33H
• Product Overview: Recombinant human SIGLEC7 protein (19-353aa), fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Specification

• Description: Predicted to enable sialic acid binding activity. Predicted to be involved in cell adhesion. Predicted to be integral component of plasma membrane. Predicted to be active in plasma membrane.
• Source: Baculovirus
• Species: Human
• Tag: His&Fc
• Protein length: 19-353aa
• Form: Liquid
• Molecular Mass: 64.2 kDa (577aa)
• AA Sequence: QKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDPVHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNVTALTHRPNILIPGTLESGCFQNLTCSVPWACEQGTPPMISWMGTSVSPLHPSTTRSSVLTLIPQPQHHGTSLTCQVTLPGAGVTTNRTIQLNVSYPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLELQVHLGDEGEFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVSGVLL
• Endotoxin: < 1 EU/μg protein by LAL
• Purity: > 90% as determined by SDS-PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade . Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/mL (determined by absorbance at 280nm)
• Storage Buffer: Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
• References: 1. Crocker., et al. (2001) Trends Immunol. 22:337-342.
  2. Nicoll G., et al. (1999) J. Biol. Chem. 274:34089-34095.

Gene Information

• Gene Name: SIGLEC7 sialic acid binding Ig like lectin 7 [ Homo sapiens (human) ]
• Official Symbol: SIGLEC7
• Synonyms: SIGLEC7; sialic acid binding Ig like lectin 7; p75; QA79; AIRM1; CD328; AIRM-1; CDw328; D-siglec; SIGLEC-7; SIGLECP2; SIGLEC19P; p75/AIRM1; sialic acid-binding Ig-like lectin 7; QA79 membrane protein; adhesion inhibitory receptor molecule 1, siglec-7; sialic acid binding immunoglobulin-like lectin 7
• Gene ID: 27036
• mRNA Refseq: NM_014385
• Protein Refseq: NP_055200
• MIM: 604410
• UniProt ID: Q9Y286