SIGLEC7
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Official Full Name
sialic acid binding Ig-like lectin 7 -
Overview
Sialic acid-binding Ig-like lectin 7 is a protein that in humans is encoded by the SIGLEC7 gene. SIGLEC7 has also been designated as CD328 (cluster of differentiation 328). -
Synonyms
SIGLEC7;sialic acid binding Ig-like lectin 7;sialic acid-binding Ig-like lectin 7;CD328;p75/AIRM1;QA79;SIGLEC 7;AIRM-1;QA79 membrane protein;sialic acid binding immunoglobulin-like lectin 7;adhesion inhibitory receptor molecule 1, siglec-7;p75
Recombinant Proteins
- Rhesus macaque
- Human
- HEK293
- E.coli
- Baculovirus
- Mammalian cells
- Non
- Fc
- hIgG4
- His
- His&S
- His&Avi
- His&Fc
Involved Pathway
SIGLEC7 involved in several pathways and played different roles in them. We selected most pathways SIGLEC7 participated on our site, such as Adaptive Immune System,Immune System,Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell, which may be useful for your reference. Also, other proteins which involved in the same pathway with SIGLEC7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Immune System | BTR12,PJA1,CTSC,SIGLEC15,CFHL2,FAM49BA,TRIM22,IFIT11,ATG7,TRIM68 |
| Adaptive Immune System | AGO1,ASB10,AF251705,AGO3,KIF5B,TRIM69,NPEPPS,GRAP2A,NA,AP1G1 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | CD226,CD200,SIGLEC9,ICAM4,TREML1,RAET1E,LAIR1,KLRB1F,CRTAM,SIGLEC12 |
Protein Function
SIGLEC7 has several biochemical functions, for example, carbohydrate binding,receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SIGLEC7 itself. We selected most functions SIGLEC7 had, and list some proteins which have the same functions with SIGLEC7. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| receptor activity | ERBB3B,CD2,RTN4RL2,NPC1,KLRK1,TNFRSF11B,P2RY1,ADIPOR1B,ANPEP,CD4 |
| carbohydrate binding | GFPT2,Siglec1,Siglece,REG3A,CLEC7A,LGALS14,NCAN,GALNT2,KLRC2,KLRC1 |
Interacting Protein
SIGLEC7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SIGLEC7 here. Most of them are supplied by our site. Hope this information will be useful for your research of SIGLEC7.
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