Recombinant Human SIGLEC5 Protein (17-441), C-Fc/Avi-tagged, Biotin-labeled
| Cat.No. : | SIGLEC5-34H |
| Product Overview : | Human secreted Sialic Acid Binding Ig Like Lectin 5 (Siglec5)-Fc fusion protein, also known as CD33L2 and OBBP2, GenBank Accession No. NM_003830, a.a. 17-441, fused at the C-terminus of the Fc portion of human IgG1, with C-terminal Avi-tag, expressed in a HEK293 cell expression system and enzymatically biotinylated using Avi-tag™ technology. |
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| Description : | This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Fc&Avi |
| Form : | Aqueous buffer solution. |
| Molecular Mass : | 76 kDa |
| Protein length : | 17-441 |
| Notes : | Thaw on ice and gently mix prior to use. DO NOT VORTEX. Perform a quick spin before opening. Aliquot into small volumes and flash freeze for long term storage. Avoid multiple freeze/thaw cycles. |
| Storage : | At least 6 months at –80 centigrade. |
| Storage Buffer : | 8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol. |
| Shipping : | At -80 centigrade |
| Warning : | Avoid freeze/thaw cycles. |
| Gene Name | SIGLEC5 sialic acid binding Ig like lectin 5 [ Homo sapiens (human) ] |
| Official Symbol | SIGLEC5 |
| Synonyms | SIGLEC5; sialic acid binding Ig like lectin 5; CD170; OBBP2; CD33L2; OB-BP2; SIGLEC-5; sialic acid-binding Ig-like lectin 5; CD33 antigen-like 2; OB-binding protein 2; obesity-binding protein 2; sialic acid-binding immunoglobulin-like lectin 5 |
| Gene ID | 8778 |
| mRNA Refseq | NM_003830 |
| Protein Refseq | NP_003821 |
| MIM | 604200 |
| UniProt ID | O15389 |
Not For Human Consumption!
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