Recombinant Human SHBG Protein, His-tagged

• Cat.No.: SHBG-583H
• Product Overview: Recombinant Human SHBG(Gly224~His388) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: This gene encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. The encoded protein transports androgens and estrogens in the blood, binding each steroid molecule as a dimer formed from identical or nearly identical monomers. Polymorphisms in this gene have been associated with polycystic ovary syndrome and type 2 diabetes mellitus. Alternative splicing results in multiple transcript variants.
• Source: E. coli
• Species: Human
• Tag: His
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 23.1kDa
• Identity: Reconstitute in PBS or others
• Protein length: Gly224~His388
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others

Gene Information

• Gene Name: SHBG sex hormone-binding globulin [ Homo sapiens ]
• Official Symbol: SHBG
• Synonyms: SHBG; sex hormone-binding globulin; ABP; androgen binding protein; MGC126834; MGC138391; TEBG; sex steroid-binding protein; testosterone-binding beta-globulin; testosterone-estrogen-binding globulin; testosterone-estradiol-binding globulin; testis-specific androgen-binding protein; SBP
• Gene ID: 6462
• mRNA Refseq: NM_001040
• Protein Refseq: NP_001031
• MIM: 182205
• UniProt ID: P04278