Recombinant Human SH3GL1 protein, MYC/DDK tagged

• Cat.No.: SH3GL1-300H
• Product Overview: Recombinant Human SH3GL1 was expressed in HEK293 cells with C-terminal MYC/DDK tag. Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 41.3 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: SH3GL1 SH3-domain GRB2-like 1 [ Homo sapiens ]
• Official Symbol: SH3GL1
• Synonyms: SH3GL1; SH3-domain GRB2-like 1; endophilin-A2; CNSA1; EEN; extra 11 19 leukemia fusion; fusion partner of MLL; MGC111371; SH3 domain GRB2 like 1; SH3 containing Grb 2 like 1 protein; SH3 containing protein EEN; SH3D2B; SH3P8
• Gene ID: 6455
• mRNA Refseq: NM_003025
• Protein Refseq: NP_003016
• MIM: 601768
• UniProt ID: Q99961