Recombinant Human SGK3, GST-tagged

• Cat.No.: SGK3-142H
• Product Overview: Recombinant human SGK3 (amino acid residues 1-130), with N-terminal GST, was expressed in E.coli.

Specification

• Description: The serum and glucocorticoid-inducible protein kinase (SGK) family is made up of three isoforms, SGK1, 2, and 3, that are phosphatidylinositide-3-kinase (PI3-K)-dependent, serine/threonine kinases, with similar substrate specificity to protein kinase B (PKB). Consequently, the SGK family also regulates similar cell processes to the PKB kinases, including cell proliferation and survival (Bruhn et al., 2013)
• Source: E. coli
• Species: Human
• Tag: GST
• Form: 50 mM Tris/HCl pH7.5, 0.1 mM EGTA, 150 mM NaCl, 0.1% ?-Mercaptoethanol, 270 mM sucrose, 0.03% Brij-35, 1 mM Benzamidine, 0.2 mM PMSF.
• Molecular Mass: ~42.4 kDa
• Purity: >95% by InstantBlue™ SDS-PAGE
• Storage: 12 months at -70°C. Avoid multiple freeze/thaw cycles.
• Concentration: 4.2 mg/ml
• Protein length: 1-130 a.a.

Gene Information

• Gene Name: SGK3 serum/glucocorticoid regulated kinase family, member 3 [ Homo sapiens ]
• Official Symbol: SGK3
• Synonyms: SGK3; serum/glucocorticoid regulated kinase family, member 3; serum/glucocorticoid regulated kinase like , SGK2, SGKL; serine/threonine-protein kinase Sgk3; cytokine-independent survival kinase; CISK; SGK2; SGKL; DKFZp781N0293
• Gene ID: 23678
• mRNA Refseq: NM_001033578
• Protein Refseq: NP_001028750
• MIM: 607591
• UniProt ID: Q96BR1
• Chromosome Location: 8q12
• Pathway: Insulin Signaling, organism-specific biosystem