Recombinant Human SGCA Protein, Myc/DDK-tagged

• Cat.No.: SGCA-01H
• Product Overview: Recombinant protein of human sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) (SGCA), transcript variant 1 with a C-Myc/DDK tag was expressed in HEK293T.

Specification

• Description: This gene encodes a component of the dystrophin-glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in this gene result in type 2D autosomal recessive limb-girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 40.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Gene Information

• Gene Name: SGCA sarcoglycan alpha [ Homo sapiens (human) ]
• Official Symbol: SGCA
• Synonyms: SGCA; sarcoglycan alpha; ADL; DAG2; 50DAG; DMDA2; LGMD2D; LGMDR3; SCARMD1; adhalin; alpha-sarcoglycan; 50 kDa dystrophin-associated glycoprotein; 50kD DAG; alpha-SG; dystroglycan-2; limb girdle muscular dystrophy 2D; sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)
• Gene ID: 6442
• mRNA Refseq: NM_000023
• Protein Refseq: NP_000014
• MIM: 600119
• UniProt ID: Q16586