Recombinant Human SFRP2 protein, GST-tagged

• Cat.No.: SFRP2-224H
• Product Overview: Recombinant Human SFRP2 protein(156-295 aa), fused with GST tag, was expressed in E.coli.

Specification

• Source: E.coli
• Species: Human
• Tag: GST
• Form: The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8.). 5 % trehalose and 5 % mannitol are added as protectant before lyophilization. The elution buffer contain 100mM GSH.
• Protein length: 156-295 aa
• Purity: 85%, by SDS-PAGE with Coomassie Brilliant Blue staining.
• Storage: Short-term storage: Store at 2-8°C for (1-2 weeks).
  Long-term storage: Aliquot and store at -20°C to -80°C for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles.
• Reconstitution: Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage.
  Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage.

Gene Information

• Gene Name: SFRP2 secreted frizzled-related protein 2 [ Homo sapiens ]
• Official Symbol: SFRP2
• Synonyms: SFRP2; secreted frizzled-related protein 2; FRP 2; SARP1; SDF 5; SARP-1; sFRP-2; secreted apoptosis related protein 1; secreted apoptosis-related protein 1; FRP-2; SDF-5
• Gene ID: 6423
• mRNA Refseq: NM_003013
• Protein Refseq: NP_003004
• MIM: 604157
• UniProt ID: Q96HF1

Reviews

11/13/2021

Fast and affordable protein sequencing; great for identifying unknown proteins.

04/28/2019

Robust protein-protein interaction assays; pivotal for our experiments.

02/20/2018

High-quality protein crystallization; crucial for structural biology studies.

Q&As

How does SFRP2 expression influence stem cell differentiation and regeneration in various tissues?

SFRP2 expression plays a significant role in stem cell differentiation, contributing to tissue regeneration and repair processes.

What role does SFRP2 play in the development and progression of cardiovascular diseases, especially atherosclerosis?

In cardiovascular diseases, SFRP2 plays a role in processes like atherosclerosis, impacting vascular health and disease progression.

What is the impact of SFRP2 on angiogenesis in the context of tumor growth and metastasis?

SFRP2 influences angiogenesis in tumors, affecting tumor growth and the potential for metastasis.

How does SFRP2 interact with Wnt signaling pathways in cancer development, particularly in colorectal and breast cancers?

SFRP2 modulates Wnt signaling in cancers, with specific roles in colorectal and breast cancer development, impacting cell proliferation and migration.

How does SFRP2 modulate bone formation and resorption in osteoporosis and other bone diseases?

SFRP2 is involved in bone metabolism, affecting bone formation and resorption in diseases like osteoporosis.

What are the mechanisms by which SFRP2 contributes to fibrosis in organ systems like the heart and liver?

SFRP2 contributes to fibrosis in organs like the heart and liver, influencing tissue remodeling and function.

How does the alteration of SFRP2 expression affect adipogenesis and metabolic processes in obesity and diabetes?

Alterations in SFRP2 expression affect adipogenesis and metabolic functions, linking it to obesity and diabetes pathologies.