Recombinant Human SETX Protein, MYC/DDK-tagged

• Cat.No.: SETX-1119H
• Product Overview: Recombinant human SETX protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a protein named for its homology to the Sen1p protein of fungi which has RNA helicase activity encoded by a domain at the C-terminal end of the protein. The protein encoded by this gene contains a DNA/RNA helicase domain at its C-terminal end which suggests that it may be involved in both DNA and RNA processing. Mutations in this gene have been associated with ataxia-ocular apraxia-2 (AOA2) and an autosomal dominant form of juvenile amyotrophic lateral sclerosis (ALS4). [provided by RefSeq, Jul 2008].
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, and 10 % glycerol.
• Molecular Mass: 57.8 kDa
• Purity: >50 ug/mL as determined by microplate BCA method
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: SETX senataxin [ Homo sapiens ]
• Official Symbol: SETX
• Synonyms: ALS4; AOA2; bA479K20.2; SCAR1
• Gene ID: 23064
• mRNA Refseq: NM_015046
• Protein Refseq: NP_055861
• MIM: 608465
• UniProt ID: Q7Z333