Recombinant Human SETD8, GST-tagged

• Cat.No.: SETD8-461H
• Product Overview: Recombinant Human SET8 (amino acids 195-352) was expressed in anE.coliexpression system with N-terminal GST tag. MW = 44 kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 195-352 a.a.
• Description: Histone-lysine N-methyltransferase SETD8 is an enzyme that in humans is encoded by the SETD8 gene.
• Formulated In: 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 0.05% Tween-20, 20% glycerol, and 3 mM DTT.
• Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
• Purity: > 70%.
• Stability: >6 months at –80°C.

Gene Information

• Gene Name: SETD8 SET domain containing (lysine methyltransferase) 8 [ Homo sapiens ]
• Synonyms: SET domain containing (lysine methyltransferase) 8; SET8; KMT5A; SET07; PR-Set7; SETD8; SET domain-containing 8; PR/SET domain containing protein 8; H4-K20-specific histone methyltransferase; EC 2.1.1.43; PR/SET07; PRSET7; H4-K20-HMTase SETD8; Lysine N-methyltransferase 5A; PR/SET domain-containing protein 07; SET domain-containing protein 8
• Gene ID: 387893
• mRNA Refseq: NM_020382
• Protein Refseq: NP_065115
• MIM: 607240
• UniProt ID: Q9NQR1
• Chromosome Location: 12q24.31
• Pathway: Lysine degradation
• Function: histone-lysine N-methyltransferase activity; methyltransferase activity; protein binding; transcription corepressor activity; transferase activity