Recombinant Human SESTD1 protein, His-tagged

• Cat.No.: SESTD1-92H
• Product Overview: Recombinant Human SESTD1, fused with N-His tag, was expressed in E. coli.

Specification

• Description: May act as the primary docking protein directing membrane turn over and assembly of the transient receptor potential channels TRPC4 and TRPC5. Binds phospholipids such as phosphatidylinositol monophosphates, phosphatidylinositol diphosphates (PIP2s) and phosphatidic acid, but not less polar lipids including phosphatidylcholine, phosphatidylserine, and phosphatidylinositol. The binding to PIP2s is calcium dependent. Might be involved in the plasma membrane localization of CTNNB1.
• Source: E.coli
• Species: Human
• Tag: His
• Form: 20mM Tris.Cl, 50mM NaCl, 50% Glycerol, pH8.0.
• Molecular Mass: 28kDa(including fusion tag)
• Protein length: 240aa(including fusion tag)
• Applications: WB, ELISA, IP, antibody production, protein array
• Storage: Store at -80centigrade and avoid repeated freeze-thaw cycles

Gene Information

• Gene Name: SESTD1 SEC14 and spectrin domains 1 [ Homo sapiens ]
• Official Symbol: SESTD1
• Synonyms: SESTD1; SEC14 and spectrin domains 1; SEC14 domain and spectrin repeat-containing protein 1; DKFZp434O0515; Solo; protein Solo; huntingtin-interacting protein-like protein; SOLO
• Gene ID: 91404
• mRNA Refseq: NM_178123
• Protein Refseq: NP_835224
• UniProt ID: Q86VW0
• Chromosome Location: 2q31.3
• Function: NOT 1-phosphatidylinositol binding; phosphatidic acid binding; NOT phosphatidylcholine binding; phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol-3,5-bisphosphate binding; phosphatidylinositol-3-phosphate binding; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylinositol-4-phosphate binding; phosphatidylinositol-5-phosphate binding; NOT phosphatidylserine binding; protein binding