Recombinant Human SERPINI1 protein, His & T7-tagged

Cat.No. : SERPINI1-8003H
Product Overview : Recombinant Human SERPINI1 aa. (Thr17~Leu410 (Accession # Q99574)) fused with N-terminal His & T7 tag was produced in E. coli cells.
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Species : Human
Source : E.coli
Tag : His&T7
Protein Length : Thr17~Leu410
Description : This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 48.4kDa
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >95%
Characteristic : The isoelectric point is 4.8.
Applications : SDS-PAGE; WB; ELISA; IP
Stability : The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage Buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
Gene Name SERPINI1 serpin family I member 1 [ Homo sapiens (human) ]
Official Symbol SERPINI1
Synonyms SERPINI1; serpin family I member 1; PI12; neuroserpin; PI-12; peptidase inhibitor 12; serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1; serpin I1; serpin peptidase inhibitor clade I member 1; serpin peptidase inhibitor, clade I (neuroserpin), member 1
Gene ID 5274
mRNA Refseq NM_001122752.1
Protein Refseq NP_001116224.1
UniProt ID Q99574

Not For Human Consumption!

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