Recombinant Human SERPINB4 protein, His & T7-tagged

• Cat.No.: SERPINB4-1834H
• Product Overview: Recombinant Human SERPINB4 aa. (Leu38~Gln215) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His&T7
• Protein Length: Leu38~Gln215
• Description: The protein encoded by this gene is a member of the serpin family of serine protease inhibitors. The encoded protein is highly expressed in many tumor cells and can inactivate granzyme M, an enzyme that kills tumor cells. This protein, along with serpin B3, can be processed into smaller fragments that aggregate to form an autoantigen in psoriasis, probably by causing chronic inflammation.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 24.4kDa.
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 9.1.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage Buffer: Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
• Reconstitution: Reconstitute in sterile ddH2O.

Gene Information

• Gene Name: SERPINB4 serpin family B member 4 [ Homo sapiens (human) ]
• Official Symbol: SERPINB4
• Synonyms: TSHB; thyrotropin subunit beta; TSH-B; TSH-beta; thyroid-stimulating hormone subunit beta; thyrotropin beta chain
• Gene ID: 6318
• mRNA Refseq: NM_002974.3
• Protein Refseq: NP_002965.1
• UniProt ID: P48594