Recombinant Human SERPINB3 Protein, C-6His tagged, Biotinylated

• Cat.No.: SERPINB3-38H
• Product Overview: Biotinylated Recombinant Human Serpin B3 is produced by E.coli. The target gene encoding M1-P390 is expressed with a 6His tag at the C terminus.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: M1-P390
• Description: Serpin B3, also known as squamous cell carcinoma antigen-1 (SCCA-1), is a member of the serpin superfamily of serine protease inhibitors. Serpins are known to inhibit serine proteases and some can inhibit caspases and papain-like cysteine proteases. Serpin B3 is also a member of the subgroup ovalbumin-related serpins which takes part in the regulation of apoptosis, inflammation, angiogenesis and embryogenesis. Serpin B3 is also a tumor marker for squamous cell carcinomas in diverse areas including the cervix, head, neck and lung. Different from typical serpins, serpin B3 inhibits papain-like lysosomal cysteine proteases Cathepsin K, L, and S, while lacking inhibitory activity against serine proteases
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of 2 μM Na2HPO4, 2 μM NaH2PO4, pH7.4
• Shipping: Ambient

Gene Information

• Gene Name: SERPINB3 serpin family B member 3 [ Homo sapiens (human) ]
• Official Symbol: SERPINB3
• Synonyms: Serpin B3; Protein T4-A; Squamous cell carcinoma antigen 1; SCCA-1; serine (or cysteine)proteinase inhibitor; clade B (ovalbumin); member 3; serpin peptidase inhibitor; clade B(ovalbumin); member 3; Squamous cell carcinoma antigen 1; T4-A; SCCA1
• Gene ID: 6317
• mRNA Refseq: NM_006919
• Protein Refseq: NP_008850
• MIM: 600517
• UniProt ID: P29508