Recombinant Human Serine/Threonine Kinase 16, His-tagged

• Cat.No.: STK16-2406H
• Product Overview: Recombinant humanSTK16 protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by using conventional chromatography

Specification

• Cat. No.: STK16-2406H
• Description: STK16, also known asserine/threonine-protein kinase 16, is a membrane-associated protein kinasethat phosphorylates on serine and threonine residues. STK16 may be involvedin secretory vesicle trafficking or intracellular signaling. Also thisprotein may have a role in regulating stromal-epithelial interactions thatoccur during ductal morphogenesis in the mammary gland. It able toautophosphorylate on Tyr residue; it is however unclear whether it hastyrosine-protein kinase toward other proteins
• Form: 20mM Tris-HCl buffer(pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
• Molecular Weight: 37.2 kDa (329aa),confirmed by MALDI-TOF
• Purity: > 90% by SDS -PAGE
• Concentration: 1 mg/ml (determinedby Bradford assay)
• Sequences of aminoacids: MGSSHHHHHHSSGLVPRGSH MGSHMGHALC VCSRGTVIID NKRYLFIQKL GEGGFSYVDL VEGLHDGHFY ALKRILCHEQQDREEAQREA DMHRLFNHPN ILRLVAYCLR ERGAKHEAWL LLPFFKRGTL WNEIERLKDK GNFLTEDQILWLLLGICRGL EAIHAKGYAH RDLKPTNILL GDEGQPVLMD LGSMNQACIH VEGSRQALTL QDWAAQRCTISYRAPELFSV QSHCVIDERT DVWSLGCVLY AMMFGEGPYD MVFQKGDSVA LAVQNQLSIP QSPRHSSALRQLLNSMMTVD PHQRPHIPLL LSQLEALQPP APGQHTTQI
• Storage: Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at-20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: STK16serine/threonine kinase 16 [ Homo sapiens ]
• Official Symbol: STK16
• Synonyms: STK16; serine/threonine kinase 16;serine/threonine-protein kinase 16; MPSK; PKL12; EDPK; F52; FLJ39635; HPSK;KRCT; MGC16211; MPSK; MPSK1; Myristoylated and palmitoylated serine/threonineprotein kinase; Myristoylated and palmitoylated serine/threonine-proteinkinase; PKL12; Protein kinase expressed in day 12 fetal liver; Protein kinaseKrct; Protein kinase PKL12; Serine/threonine kinase 16; Serine/threonineprotein kinase 16; Serine/threonine-protein kinase 16; Stk16; STK16_HUMAN;TGF beta stimulated factor 1; TGF-beta-stimulated factor 1; TGFB stimulatedfactor 1; Transforming growth factor beta stimulated factor 1; TSF-1; TSF1;hPSK; TSF-1; OTTHUMP00000205887; OTTHUMP00000205888; OTTHUMP00000205889;OTTHUMP00000205890; OTTHUMP00000205891; protein kinase PKL12; TGF-beta-stimulatedfactor 1; tyrosine-protein kinase STK16; protein kinase expressed in day 12fetal liver; myristoylated and palmitoylated serine/threonine-protein kinase;KRCT; TSF1
• Gene ID: 8576
• mRNA Refseq: NM_001008910
• Protein Refseq: NP_001008910
• MIM: 604719
• Uniprot ID: O75716
• Chromosome Location: 2q35
• Function: ATP binding; DNA binding;non-membrane spanning protein tyrosine kinase activity; nucleotide binding;protein binding