Recombinant Human SEPT7 Protein, His-tagged

• Cat.No.: SEPT7-759H
• Product Overview: Recombinant human SEPT7 protein, fused to His tag at N-terminus, was expressed in E. coli.

Specification

• Description: This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19. [provided by RefSeq, Jul 2011].
• Source: E. coli
• Species: Human
• Tag: His
• Form: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
• Molecular Mass: 50.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: septin 7[ Homo sapiens ]
• Official Symbol: SEPT7
• Synonyms: CDC10; CDC3; NBLA02942; SEPT7A
• Gene ID: 989
• mRNA Refseq: NM_001788.5
• Protein Refseq: NP_001779
• MIM: 603151
• UniProt ID: Q16181