Recombinant Human SEMA3A protein, His/Fc-tagged
| Cat.No. : | SEMA3A-852H |
| Product Overview : | Recombinant Human SEMA3A(Met 1-Val 771) fused with the His tag and Fc region of human IgG1 at C-terminal was expressed in HEK293. |
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| Source : | HEK293 |
| Species : | Human |
| Tag : | His&Fc |
| Form : | Lyophilized from sterile PBS, pH 7.4 |
| Molecular Mass : | The recombinant human SEMA3A/Fc is a disulfide-linked homodimer. The reduced monomer consists of 994 amino acids and has a predicted molecular mass of 114 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh SEMA3A/Fc monomer is approximately 170-190 kDa due to glycosylation. |
| Protein length : | Met 1-Val 771 |
| Endotoxin : | < 1.0 eu per μg of the protein as determined by the LAL method. |
| Stability : | Samples are stable for up to twelve months from date of receipt at -70 centigrade. |
| Storage : | Store it under sterile conditions at -20 centigrade~-70 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
| Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4 centigrade before opening to recover the entire contents. |
| Gene Name | SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A [ Homo sapiens ] |
| Official Symbol | SEMA3A |
| Synonyms | SEMA3A; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A; SEMAD; semaphorin-3A; coll 1; Hsema I; sema III; SEMA1; SemD; collapsin 1; semaphorin D; semaphorin L; semaphorin III; SEMAL; coll-1; Hsema-I; SEMAIII; Hsema-III; MGC133243; |
| Gene ID | 10371 |
| mRNA Refseq | NM_006080 |
| Protein Refseq | NP_006071 |
| MIM | 603961 |
| UniProt ID | Q14563 |
| Chromosome Location | 7p12.1 |
| Pathway | Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; Axon guidance, organism-specific biosystem; CRMPs in Sema3A signaling, organism-specific biosystem; Developmental Biology, organism-specific biosystem; SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion, organism-specific biosystem; Sema3A PAK dependent Axon repulsion, organism-specific biosystem; |
| Function | chemorepellent activity; receptor activity; |
Not For Human Consumption!
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