Recombinant Human Secretogranin V (7B2 Protein), His-tagged

• Cat.No.: SCG5-2795H
• Product Overview: Recombinant human SCG5 protein (27-212 aa), fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 27-212 a.a.
• Description: SCG5, also known as Neuroendocrine protein 7B2, is widely distributed in neuroendocrine tissues. It functions as a chaperone protein for the proprotein convertase PC2 and is required for the production of an active PC2 enzyme.
• Sequences: MYSPRTPDRV SEADIQRLLH GVMEQLGIAR PRVEYPAHQA MNLVGPQSIE GGAHEGLQHL GPFGNIPNIV AELTGDNIPK DFSEDQGYPD PPNPCPVGKT ADDGCLENTP DTAEFSREFQ LHQHLSDPEH DYPGLGKWNK KLLYEKMKGG ERRKRRSVNP YLQGQRLDNV VAKKSVPHFS DEDKDPELEH HHHHH.
• Form: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.1M Nacl, 1mM DTT, 20% glycerol, 0.1mM PMSF.
• Molecular Weight: 22.0 kDa (195aa),confirmed by MALDI-TOF.
• Purity: > 85% by SDS – PAGE.
• Concentration: 0.5 mg/ml (determined by Bradford assay).
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: SCG5 secretogranin V (7B2 protein) [ Homo sapiens ]
• Synonyms:
  SCG5;secretogranin V (7B2 protein); OTTHUMP00000215366; OTTHUMP00000215367; OTTHUMP00000215368; neuroendocrine protein 7B2; pituitary polypeptide; prohormone convertase chaperone; secretogranin-5; secretory granule endocrine protein I; secretory granule, neuroendocrine protein 1 (7B2 protein); 7B2; SgV; P7B2; SGNE1
• Gene ID: 6447
• mRNA Refseq: NM_001144757
• Protein Refseq: NP_001138229
• MIM: 173120
• UniProt ID: P05408
• Chromosome Location: 15q13-q14
• Function: GTP binding; enzyme inhibitor activity; protein binding; unfolded protein binding