Recombinant Human SCGB1A1 Protein, MYC/DDK-tagged

• Cat.No.: SCGB1A1-464H
• Product Overview: Recombinant human SCGB1A1 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Description: This gene encodes a member of the secretoglobin family of small secreted proteins. The encoded protein has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma. [provided by RefSeq, May 2010].
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 9.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: secretoglobin family 1A member 1 [ Homo sapiens ]
• Official Symbol: SCGB1A1
• Synonyms: CC10; CC16; CCPBP; CCSP; UGB; UP-1; UP1
• Gene ID: 7356
• mRNA Refseq: NM_003357.4
• Protein Refseq: NP_003348.1
• MIM: 192020
• UniProt ID: P11684

Reviews

02/07/2022

Precise antibody validation, enhances our immunoprecipitation accuracy.

06/07/2019

Efficient protein purification, delivers high yield and purity consistently.

03/25/2019

Timely protein expression optimization, greatly boosts our research efforts.

Q&As

How does SCGB1A1 influence the response of lung tissue to environmental pollutants and allergens?

SCGB1A1 helps protect lung tissue from environmental pollutants and allergens, reducing the risk of damage and inflammation.

What are the mechanisms by which SCGB1A1 modulates immune cell recruitment and activation in the lungs?

SCGB1A1 influences immune cell behavior in the lungs, affecting responses to infections and inflammation.

How does SCGB1A1 (Secretoglobin Family 1A Member 1) function in respiratory tract defense and lung homeostasis?

SCGB1A1 is important for respiratory defense, contributing to the maintenance of lung health and protection against irritants.

What is the impact of SCGB1A1 in asthma and chronic obstructive pulmonary disease (COPD) pathogenesis?

SCGB1A1 is implicated in the pathogenesis of asthma and COPD, influencing airway inflammation and reactivity.

How do alterations in SCGB1A1 expression or function affect respiratory infections and healing after lung injury?

Changes in SCGB1A1 expression can impact the body's ability to fight respiratory infections and heal after lung injuries.

What role does SCGB1A1 play in modulating inflammatory responses in chronic lung diseases?

SCGB1A1 modulates inflammation in chronic lung conditions, potentially impacting disease progression.

How does SCGB1A1 contribute to mucus production and airway protection?

SCGB1A1 plays a role in mucus production, essential for trapping and clearing pathogens and particles from the airways.