Recombinant Human SCCA2

• Cat.No.: SCCA2-70H
• Product Overview: Recombinant Human Squamous Cell Carcinoma Antigen 2 was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: Non
• Description: Squamous cell carcinoma antigen (SCCA), a member of the serine protease inhibitor (serpin) family, is a subfraction of the tumor associated antigen TA-4, is a glycoprotein, with a molecular weight between 42 to 48 kDa. SCCA2 is a serological marker for squamous cell carcinomas (SCC). Elevated serum levels are correlated with the clinical stage of the disease.Schneider et al. demonstrated that 18q21.3 contains a cluster of serine proteinase inhibitors, or serpins, including a tandem duplication of the squamous cell carcinoma antigen (SCCA) gene and 2 other members of the ovalbumin family of serine proteinase inhibitors, plasminogen activator inhibitor type 2 and maspin (protease inhibitor-5). Schneider et al. presented evidence that the neutral and acidic forms of SCCA are encoded by SCCA1 and SCCA2, respectively.
• Form: The protein solution is in 0.05M phosphate buffer containing 0.15M NaCl and 0.09% NaN3 pH 7.5. Filtered through a 0.4μM membrane.
• Molecular Mass: 9.3kDa
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >95 % as determined by SDS-PAGE
• Applications: Western blotting, ELISA
• Storage: Store it under sterile conditions at -20℃ to -121℃ upon receiving.Recommend to aliquot the protein into smaller quantities for optimal storage.