Recombinant Human S100P, His-tagged

• Cat.No.: S100P-31372TH
• Product Overview: Recombinant full-length Human S100P , with N terminal His tag, 115 amino acids with tag, MWt 12.6kDa.

Specification

• Description: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 4p16. This protein, in addition to binding Ca2+, also binds Zn2+ and Mg2+. This protein may play a role in the etiology of prostate cancer.
• Conjugation: HIS
• Source: E. coli
• Tissue specificity: Up-regulated in various pancreatic ductal adenocarcinomas and pancreatic intraepithelial neoplasias.
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 20% Glycerol, 50mM Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MTELETAMGM IIDVFSRYSG SEGSTQTLTK GELKVLMEKE LPGFLQSGKD KDAVDKLLKD LDANGDAQVDFSEFIVFVAA ITSACHKYFE KAGLK
• Sequence Similarities: Belongs to the S-100 family.Contains 2 EF-hand domains.

Gene Information

• Gene Name: S100P S100 calcium binding protein P [ Homo sapiens ]
• Official Symbol: S100P
• Synonyms: S100P; S100 calcium binding protein P; protein S100-P
• Gene ID: 6286
• mRNA Refseq: NM_005980
• Protein Refseq: NP_005971
• MIM: 600614
• Uniprot ID: P25815
• Chromosome Location: 4p16
• Function: calcium ion binding; calcium-dependent protein binding; magnesium ion binding; protein binding