Recombinant Human RXRG protein, His & T7-tagged

• Cat.No.: RXRG-1081H
• Product Overview: Recombinant Human RXRG aa. (Pro12~Ala220 (Accession # P48443) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His&T7
• Protein Length: Pro12~Ala220
• Description: This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 26.0kDa.
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 9.5.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: RXRG retinoid X receptor gamma [ Homo sapiens (human) ]
• Official Symbol: RXRG
• Synonyms: RXRG; retinoid X receptor gamma; RXRC; NR2B3; retinoic acid receptor RXR-gamma; nuclear receptor subfamily 2 group B member 3
• Gene ID: 6258
• mRNA Refseq: NM_001256571.1
• Protein Refseq: NP_001243500.1
• UniProt ID: P48443