Recombinant Full Length Human RXRG Protein

• Cat.No.: RXRG-451HF
• Product Overview: Recombinant full length Human Retinoid X Receptor gamma with N terminal proprietary tag; Predicted MWt 77.00 kDa incusive of tag.

Specification

• Description: This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described.
• Source: In Vitro Cell Free System
• Species: Human
• Form: Liquid
• Molecular Mass: 77.000kDa inclusive of tags
• Protein length: 463 amino acids
• AA Sequence: MYGNYSHFMKFPAGYGGSPGHTGSTSMSPSAALSTGKPMD SHPSYTDTPVSAPRTLSAVGTPLNALGSPYRVITSAMGPP SGALAAPPGINLVAPPSSQLNVVNSVSSSEDIKPLPGLPG IGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCK GFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQYCRYQKCL VMGMKREAVQEERQRSRERAESEAECATSGHEDMPVERIL EAELAVEPKTESYGDMNMENSTNDPVTNICHAADKQLFTL VEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVS VQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKD MQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYAT LEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFF KLIGDTPIDTFLMEMLETPLQIT
• Purity: Proprietary Purification
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles.
• Storage Buffer: pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione.

Gene Information

• Gene Name: RXRG retinoid X receptor, gamma [ Homo sapiens ]
• Official Symbol: RXRG
• Synonyms: RXRG; retinoid X receptor, gamma; retinoic acid receptor RXR-gamma; NR2B3
• Gene ID: 6258
• mRNA Refseq: NM_006917
• Protein Refseq: NP_008848
• MIM: 180247
• UniProt ID: P48443