Recombinant Human RXRA, His-tagged

• Cat.No.: RXRA-1151H
• Product Overview: Recombinant Human RXRA(NP_001278849.1), fused to His-tag, was expressed in E. coli.

Specification

• Description: Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors function as transcription factors by binding as homodimers or heterodimers to specific sequences in the promoters of target genes. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Alternative splicing of this gene results in multiple transcript variants.
• Source: E. coli
• Species: Human
• Tag: His
• Form: 20mM Tris, 0.15M NaCl (pH8.0)
• Molecular Mass: The protein has a calculated MW of 38 kDa.
• AA Sequence: MGSSHHHHHHSSGLVPRGSHMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAELAVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT
• Purity: ＞95%, by SDS-PAGE
• Storage: Store it under sterile conditions at -20 to -80 ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 0.2 mg/ml
• Protein length: 198-462 a.a.

Gene Information

• Gene Name: RXRA retinoid X receptor alpha [ Homo sapiens (human) ]
• Official Symbol: RXRA
• Synonyms: NR2B1
• Gene ID: 6256
• mRNA Refseq: NM_001291920.2
• Protein Refseq: NP_001278849.1
• MIM: 180245
• UniProt ID: P19793