Recombinant Human RXRA Protein, His-tagged

• Cat.No.: RXRA-2667H
• Product Overview: Recombinant Human RXRA Protein (Ser129-Gly212) with a N-His tag was expressed in E. coli.

Specification

• Description: Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors function as transcription factors by binding as homodimers or heterodimers to specific sequences in the promoters of target genes. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Alternative splicing of this gene results in multiple transcript variants.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 13.6 kDa
  Accurate Molecular Mass: 14 kDa
• Protein length: 129-212 a.a.
• Endotoxin: <1.0 EU per 1µg (determined by the LAL method).
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: RXRA retinoid X receptor, alpha [ Homo sapiens (human) ]
• Official Symbol: RXRA
• Synonyms: RXRA; retinoid X receptor, alpha; retinoic acid receptor RXR-alpha; NR2B1; nuclear receptor subfamily 2 group B member 1; retinoid X nuclear receptor alpha; FLJ00280; FLJ00318; FLJ16020; FLJ16733; MGC102720
• Gene ID: 6256
• mRNA Refseq: NM_002957
• Protein Refseq: NP_002948
• MIM: 180245
• UniProt ID: P19793