Recombinant Human RUFY4 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: RUFY4-1811H
• Product Overview: RUFY4 MS Standard C13 and N15-labeled recombinant protein (NP_940885) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Positively regulates macroautophagy in primary dendritic cells. Increases autophagic flux, probably by stimulating both autophagosome formation and facilitating tethering with lysosomes. Binds to phosphatidylinositol 3-phosphate (PtdIns3P) through its FYVE-type zinc finger.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 44.9 kDa
• AA Sequence: MFSESRCSSSTQTQGRRPRKNKDAPKKIPAAYGGPENVQIEDSHTSQAICLQDAPSGQQLAGLPRSQQQRHLPFFLEKKGESSRKHRYPQSMWEPEGKELQLDQEERAPWIEIFLGNSTPSTQGQGKGAMGTQKEVIGMEAEVTGVLLVAEGQRTTEGTHKKEAEWSHVQRLLMPSPRGAVEGAVSGSRQGSGGSSILGEPWVLQGHATKEDSTVENPQVQTEVTLVARREEQAEVSLQDEIKSLRLGLRKAEEQAQRQEQLLREQEGELQALREQLSRCQEERAELQAQLEQKQQEAERRDAMYQEELGGQRDLVQAMKRRVLELIQEKDRLWQRLQHLSSMAPECCVACSKIFGRFSRRYPCRLCGGLLCHACSMDYKKRDRCCPPCAQGREAQVTTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: RUFY4 RUN and FYVE domain containing 4 [ Homo sapiens (human) ]
• Official Symbol: RUFY4
• Synonyms: RUFY4; RUN and FYVE domain containing 4; RUN and FYVE domain-containing protein 4; FLJ46536
• Gene ID: 285180
• mRNA Refseq: NM_198483
• Protein Refseq: NP_940885
• UniProt ID: Q6ZNE9