Recombinant Human RRAS, His-tagged

• Cat.No.: RRAS-2360H
• Product Overview: Recombinant human RRAS protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques. 25.3 kDa (235aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-215 a.a.
• Description: RRAS, also known as ras-related protein R-Ras, belongs to the Ras family which functions in signal transduction pathways. This protein has been shown to interact with RASSF5, NCK1, Bcl-2, ARAF and RALGDS. RRAS can bind GTP and GDP, and it has intrinsic GTPase activity. It also regulates the organization of the actin cytoskeleton.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl.
• Purity: > 85% by SDS - PAGE.
• Concentration: 0.5 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MSSGAASGTG RGRPRGGGPG PGDPPPSETH KLVV VGGGGV GKSALTIQFI QSYFVSDYDP TIEDSYTKICSVDGIPARLD ILDT AGQ EEF GAMREQYMRA GHGFLLVFAI NDRQSFNEVG KLFTQILRVK DRDDFPVVLV GNKADLESQR QVPRSEASAFGASHHVAYFE ASAKLRLNVD EAFEQLVRAV RKY QE QELPP SPPSAPRKKG GGCPC.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: RRAS related RAS viral (r-ras) oncogene homolog [ Homo sapiens ]
• Synonyms: related RAS viral (r-ras) oncogene homolog; RRAS; ras-related protein R-Ras; p23; Oncogene RRAS
• Gene ID: 6237
• mRNA Refseq: NM_006270
• Protein Refseq: NP_006261
• MIM: 165090
• UniProt ID: P10301
• Chromosome Location: 19q13.3-qter
• Pathway: MAPK signaling pathway; Regulation of actin cytoskeleton; Tight junction; Axon guidance
• Function: protein binding; nucleotide binding; GTPase activity; GTP binding; GDP binding