Recombinant Human RPS6KA1
Cat.No. : | RPS6KA1-30110TH |
Product Overview : | Recombinant full length RSK1 p90 protein (Human), was expressed by baculovirus in Sf9 insect cells using a N-terminal tag, MW 108 kDa. |
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Species : | Human |
Tag : | Non |
Description : | This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
Form : | Liquid |
Storage buffer : | Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, pH 7.5 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.Contains 1 AGC-kinase C-terminal domain.Contains 2 protein kinase domains. |
Full Length : | Full L. |
Gene Name | RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 [ Homo sapiens ] |
Official Symbol | RPS6KA1 |
Synonyms | RPS6KA1; ribosomal protein S6 kinase, 90kDa, polypeptide 1; ribosomal protein S6 kinase, 90kD, polypeptide 1; ribosomal protein S6 kinase alpha-1; HU 1; RSK; RSK1; |
Gene ID | 6195 |
mRNA Refseq | NM_001006665 |
Protein Refseq | NP_001006666 |
MIM | 601684 |
Uniprot ID | Q15418 |
Chromosome Location | 1p |
Pathway | Activated TLR4 signalling, organism-specific biosystem; Activation of NMDA receptor upon glutamate binding and postsynaptic events, organism-specific biosystem; Axon guidance, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; CREB phosphorylation, organism-specific biosystem; |
Function | ATP binding; cysteine-type endopeptidase inhibitor activity involved in apoptotic process; magnesium ion binding; nucleotide binding; protein serine/threonine kinase activity; |
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◆ Cell & Tissue Lysates | ||
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Not For Human Consumption!
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