Recombinant Human RPS19 Protein, His-tagged

• Cat.No.: RPS19-693H
• Product Overview: Recombinant Human RPS19(Pro2-His145) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 2-145 a.a.
• Description: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
• Form: Lyophilized from a 0.2 µM filtered solution of 20mM Phosphate buffer, 150mM NaCl, pH 7.4. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
• Molecular Mass: 16.1 kDa
• Endotoxin: < 0.1 EU per µg protein as determined by LAL test
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: Resuspend the protein to the desired concentration in proper buffer.

Gene Information

• Gene Name: RPS19 ribosomal protein S19 [ Homo sapiens ]
• Official Symbol: RPS19
• Synonyms: RPS19; ribosomal protein S19; 40S ribosomal protein S19; DBA; Diamond Blackfan anemia; S19; DBA1
• Gene ID: 6223
• mRNA Refseq: NM_001022
• Protein Refseq: NP_001013
• MIM: 603474
• UniProt ID: P39019