Recombinant Human RPRD1A Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: RPRD1A-2264H
• Product Overview: RPRD1A MS Standard C13 and N15-labeled recombinant protein (NP_060640) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a cell-cycle and transcription regulatory protein. The encoded protein interacts with the cell cycle inhibitor cyclin-dependent kinase 4 inhibitor B and may function as a negative regulator of G(1)/S phase progression. This protein also forms homo- and hetrodimers with the protein, regulation of nuclear pre-mRNA domain-containing protein 1B, to form a scaffold that interacts with the C-terminal domain of RNA polymerase II subunit B1 and regulates several aspects of transcription. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 16.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 35.5 kDa
• AA Sequence: MSAFSEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKAKPNRKLTFLYLANDVIQNSKRKGPEFTKDFAPVIVEAFKHVSSETDESCKKHLGRVLSIWEERSVYENDVLEQLKQALYGDKKPRKRTYEQIKVDENENCSSLGSPSEPPQTLDLVRALQDLENAASGDAAVHQRIASLPVEVQEVSLLDKITDKESGERLSKMVEDACMLLADYNGRLAAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEEYKRKLARVSLVRKELRSRIQSLPDLSRLPNVTGSHMHLPFAGDIYSEDTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: RPRD1A regulation of nuclear pre-mRNA domain containing 1A [ Homo sapiens (human) ]
• Official Symbol: RPRD1A
• Synonyms: RPRD1A; regulation of nuclear pre-mRNA domain containing 1A; regulation of nuclear pre-mRNA domain-containing protein 1A; cyclin dependent kinase 2B inhibitor related protein; Cyclin dependent kinase inhibitor 2B related protein (p15INK4B related protein); FLJ10656; HsT3101; P15RS; p15INK4B-related protein; cyclin-dependent kinase 2B-inhibitor-related protein; Cyclin-dependent kinase inhibitor 2B-related protein (p15INK4B-related protein); MGC19513
• Gene ID: 55197
• mRNA Refseq: NM_018170
• Protein Refseq: NP_060640
• MIM: 610347
• UniProt ID: Q96P16