Recombinant Human RPA1, MYC/DDK-tagged

• Cat.No.: RPA1-31146H
• Product Overview: Recombinant Human RPA1 fused with MYC/DDK tag at C-terminal, was expressed in HEK293 Cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: Replication protein A 70 kDa DNA-binding subunit is a protein that in humans is encoded by the RPA1 gene.
• Molecular Mass: 68 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Storage buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Concentration: >50 ug/mL as determined by microplate BCA method
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Storage: Store at -800C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
• OfficialSymbol: RPA1

Gene Information

• Gene Name: RPA1 replication protein A1, 70kDa [ Homo sapiens ]
• Synonyms: RPA1; replication protein A1, 70kDa; replication protein A 70 kDa DNA-binding subunit; HSSB; RF-A; RP-A; REPA1; RPA70; MST075; RP-A p70; RF-A protein 1; replication factor A protein 1; single-stranded DNA-binding protein
• Gene ID: 6117
• mRNA Refseq: NM_002945
• Protein Refseq: NP_002936
• MIM: 179835
• UniProt ID: P27694
• Chromosome Location: 17p13.3
• Pathway: Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Assembly of the RAD51-ssDNA nucleoprotein complex; Cell Cycle Checkpoints; Cell Cycle, Mitotic
• Function: chromatin binding; metal ion binding; protein binding; single-stranded DNA binding