Recombinant Human RLIM Protein, His-tagged

• Cat.No.: RLIM-498H
• Product Overview: Recombinant Human RLIM, transcript variant 2, fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: The protein encoded by tHis gene is a RING-H2 zinc finger protein. It has been shown to be an E3 ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. THis protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Multiple alternatively spliced variants, encoding the same protein, have been identified.
• Form: 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.
• Molecular Mass: 68.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: RLIM ring finger protein, LIM domain interacting [ Homo sapiens ]
• Official Symbol: RLIM
• Synonyms: RLIM; ring finger protein, LIM domain interacting; ring finger protein 12 , RNF12; E3 ubiquitin-protein ligase RLIM; LIM domain interacting ring finger protein; MGC15161; NY REN 43; ring zinc finger protein NY REN 43antigen; R-LIM; ring finger protein 12; E3 ubiquitin-protein ligase RNF12; renal carcinoma antigen NY-REN-43; RING finger LIM domain-binding protein; ring zinc finger protein NY-REN-43antigen; LIM domain-interacting RING finger protein; ring zinc finger LIM domain binding protein; RNF12; NY-REN-43; FLJ25923; FLJ41093; FLJ42887; FLJ45986; DKFZp686N06224
• Gene ID: 51132
• mRNA Refseq: NM_016120
• Protein Refseq: NP_057204
• MIM: 300379
• UniProt ID: Q9NVW2