Recombinant Human RIPPLY2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: RIPPLY2-1935H
• Product Overview: RIPPLY2 MS Standard C13 and N15-labeled recombinant protein (NP_001009994) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a nuclear protein that belongs to a novel family of proteins required for vertebrate somitogenesis. Members of this family have a tetrapeptide WRPW motif that is required for interaction with the transcriptional repressor Groucho and a carboxy-terminal Ripply homology domain/Bowline-DSCR-Ledgerline conserved region required for transcriptional repression. Null mutant mice die soon after birth and display defects in axial skeleton segmentation due to defective somitogenesis. Alternative splicing results in multiple transcript variants.
• Molecular Mass: 13.9 kDa
• AA Sequence: MENAGGAEGTESGAAACAATDGPTRRAGADSGYAGFWRPWVDAGGKKEEETPNHAAEAMPDGPGMTAASGKLYQFRHPVRLFWPKSKCYDYLYQEAEALLKNFPIQATISFYEDSDSEDEIEDLTCENTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: RIPPLY2 ripply transcriptional repressor 2 [ Homo sapiens (human) ]
• Official Symbol: RIPPLY2
• Synonyms: RIPPLY2; ripply transcriptional repressor 2; SCDO6; C6orf159; dJ237I15.1; protein ripply2; ripply2 homolog
• Gene ID: 134701
• mRNA Refseq: NM_001009994
• Protein Refseq: NP_001009994
• MIM: 609891
• UniProt ID: Q5TAB7