Recombinant Human RIPK3 Protein, GST-tagged

• Cat.No.: RIPK3-894H
• Product Overview: Recombinant Human RIPK3 fused with GST tag at N-terminal was expressed in Sf9 cells.

Specification

• Description: The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
• Source: Sf9 cells
• Tag: GST
• Form: 50mM Tris-HCl, pH8.0, 300mM NaCl, 10% glycerol.
• Molecular Mass: 56.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: RIPK3 receptor-interacting serine-threonine kinase 3 [ Homo sapiens ]
• Official Symbol: RIPK3
• Synonyms: RIPK3; receptor-interacting serine-threonine kinase 3; receptor-interacting serine/threonine-protein kinase 3; RIP3; RIP-3; RIP-like protein kinase 3; receptor interacting protein 3; receptor-interacting protein 3
• Gene ID: 11035
• mRNA Refseq: NM_006871
• Protein Refseq: NP_006862
• MIM: 605817
• UniProt ID: Q9Y572