Recombinant Human RIPK3, GST-tagged

• Cat.No.: RIPK3-2899H
• Product Overview: RecombinantHuman RIPK3 produced by wheat germ expression system in vitro contains GSTtag at N-terminus and is purified by glutathione sepharose 4 fast flow.

Specification

• Species: Human
• Source: Wheat Germ
• Tag: GST
• Description: The productof this gene is a member of the receptor-interacting protein (RIP) family ofserine/threonine protein kinases, and contains a C-terminal domain uniquefrom other RIP family members. The encoded protein is predominantly localizedto the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent onnovel nuclear localization and export signals. It is a component of the tumornecrosis factor (TNF) receptor-I signaling complex, and can induce apoptosisand weakly activate the NF-kappaB transcription factor.
• Applications: Kinase Assay; ELISA ; Antibody Production; WesternBlot; Protein Array
• StorageBuffer: 50mM Tris-HCl, 10 mM reduced Glutathione, pH8.0 in the elution buffer.
• Storage: Store at -80℃. Aliquot toavoid repeated freezing and thawing.
• OfficialSymbol: RIPK3

Gene Information

• Gene Name: RIPK3 receptor-interactingserine-threonine kinase 3 [ Homo sapiens ]
• Synonyms: receptor-interactingserine-threonine kinase 3; RIP3; Receptor-interacting protein 3; RIP-3; RIP-likeprotein kinase 3; OTTHUMP00000164791; receptor interacting protein3; receptor-interactingserine/threonine-protein kinase 3; EC 2.7.11.1; receptor-interactingserine/threonine-protein kinase 3
• Gene ID: 11035
• mRNA Refseq: NM_006871
• Protein Refseq: NP_006862
• MIM: 605817
• UniProt ID: Q9Y572
• Chromosome Location: 14q12
• Pathway: CytosolicDNA-sensing pathway; Immune System; Innate Immune System
• Function: ATPbinding; nucleotide binding; nucleotide binding