Recombinant Human ribosomal protein S18, His-tagged

• Cat.No.: RPS18-297H
• Product Overview: RPS18, 1-152aa, Human, His tag, E.coli

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-152 a.a.
• Description: 40S ribosomal protein S18, also known as RPS18, belongs to the ribosomal protein S13P family. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. RPS18 is a known binding partner of Cofilin and has been suggested to be a novel substrate for CaMKII. Recombinant human RPS18 protein, fused to His-tag at N-terminus, was expressed in E.coli.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol
• Molecular Mass: 20.1 kDa (175aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSLVIPE KFQHILRVLN TNIDGRRKIA FAITAIKGVG RRYAHVVLRK ADIDLTKRAG ELTEDEVERV ITIMQNPRQY KIPDWFLNRQ KDVKDGKYSQ VLANGLDNKL REDLERLKKI RAHRGLRHFW GLRVRGQHTK TTGRRGRTVG VSKKK
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: RPS18 ribosomal protein S18 [ Homo sapiens ]
• Official Symbol: RPS18
• Synonyms: RPS18; ribosomal protein S18; D6S218E; 40S ribosomal protein S18; HKE3; KE 3; KE3; S18; rhabdomyosarcoma antigen MU-RMS-40.21; KE-3; MGC117351; MGC126835; MGC126837
• Gene ID: 6222
• mRNA Refseq: NM_022551
• Protein Refseq: NP_072045
• MIM: 180473
• UniProt ID: P62269
• Chromosome Location: 6p21.3
• Pathway: Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S, organism-specific biosystem; Cap-dependent Translation Initiation, organism-specific biosystem; Cytoplasmic Ribosomal Proteins, organism-specific biosystem; Disease, organism-specific biosystem; Eukaryotic Translation Elongation, organism-specific biosystem; Eukaryotic Translation Initiation, organism-specific biosystem; Eukaryotic Translation Termination, organism-specific biosystem
• Function: RNA binding; molecular_function; rRNA binding; structural constituent of ribosome