Recombinant Human Ribonucleotide Reductase M2, T7-tagged

• Cat.No.: RRM2-820H
• Product Overview: Recombinant RRM2 protein, fused to T7-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques, 44878Da (389aa).

Specification

• Cat. No.: RRM2-820H
• Description: Ribonucleoside-diphosphate reductase subunit M2, also known as ribonucleotide reductase small subunit, is anenzymethat in humans is encoded by the RRM2gene.
• Sequences of amino acids: MLSLRVPLP ITDPQQLQLS PLKGLSLVDK ENTPPALSGT RVLASKTARR IFQEPTEPKT KAAAPGVEDE PLLRENPRRF VIFPIEYHDI WQMYKKAEAS FWTAEEVDLS KDIQHWESLK PEERYEISHV LAFFAASDGI VNENLVERFS QEVQITEARC FYGFQIAMEN IHSEMYSLLI DTYIKDPKER EFLFNAIETM PCVKKKADWA LRWIGDKEAT YGERVVAFAA VEGIFFSGSF ASIFWLKKRG LMPGLTFSNE LISRDEGLHC DFACLMFKHL VHKPSEERVR EIIINAVRIE QEELTEALPV KLIGMNCTLM KQYIEFVADR LMLELGFSKV FRVENPFDFM ENISLEGKTN FFEKRVGEYQ RMGVMSSPTE NSFTLDADF
• Formulation: 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3. 10mM DTT
• Clonality: N/A
• Purity: 95% by SDS - PAGE
• Applications: MS. SDS

Gene Information

• Gene Name: RRM2 ribonucleotide reductase M2 [Homo sapiens]
• Synonyms: RRM2; RR2M; RR2; R2; EC 1.17.4.1; ribonucleotide reductase M2; ribonucleotide reductase M2 polypeptide; ribonucleoside-diphosphate reductase subunit M2; Ribonucleotide reductase small chain; Ribonucleotide reductase small subunit; OTTHUMP00000115511; OTTHUMP00000214026
• Gene ID: 6241
• mRNA Refseq: NM_001034
• Protein Refseq: NP_001025
• MIM: 180390
• UniProt ID: P31350
• Chromosome Location: 2P25-P24
• Pathway: Glutathione metabolism; Metabolic pathways; Purine metabolism; Pyrimidine metabolism; p53 signaling pathway
• Function: Oxidoreductase activity; protein binding; ribonucleoside-diphosphate reductase activity; ribonucleoside-diposphate reductase activity; transition metal ion binding