Recombinant Human RGS18 Protein, His-tagged

• Cat.No.: RGS18-1183H
• Product Overview: Recombinant human RGS18 protein, fused to His tag at N-terminus, was expressed in E. coli.

Specification

• Description: This gene encodes a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008].
• Source: E. coli
• Species: Human
• Tag: His
• Form: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl. Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
• Molecular Mass: 27.6 kDa
• Purity: >50 ug/mL as determined by microplate BCA method
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: RGS18 regulator of G-protein signaling 18 [ Homo sapiens ]
• Official Symbol: RGS18
• Synonyms: RGS13; RGS13
• Gene ID: 64407
• mRNA Refseq: NM_130782
• Protein Refseq: NP_570138
• MIM: 607192
• UniProt ID: Q9NS28