Recombinant Human RGS13 Protein, His-tagged

• Cat.No.: RGS13-688H
• Product Overview: Recombinant Human RGS13, transcript variant 2, fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: The protein encoded by this gene is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown. Two transcript variants encoding the same isoform exist.
• Form: 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1%Sarkosyl.
• Molecular Mass: 19 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: RGS13 regulator of G-protein signaling 13 [ Homo sapiens ]
• Official Symbol: RGS13
• Synonyms: RGS13; regulator of G-protein signaling 13; regulator of G protein signalling 13; regulator of G-protein signalling 13; MGC17173
• Gene ID: 6003
• mRNA Refseq: NM_002927
• Protein Refseq: NP_002918
• MIM: 607190
• UniProt ID: O14921