Recombinant Human RFXAP cell lysate

• Cat.No.: RFXAP-1496HCL

Specification

• Species: Human
• Tag: Non
• Description: Major histocompatibility (MHC) class II molecules are transmembrane proteins that have a central role in development and control of the immune system. The protein encoded by this gene, along with regulatory factor X-associated ankyrin-containing protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates their transcription. Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls the cell type specificity and inducibility of MHC class II gene expression. Mutations in this gene have been linked to bare lymphocyte syndrome type II, complementation group D. Transcript variants utilizing different polyA signals have been found for this gene.
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: RFXAP regulatory factor X-associated protein [ Homo sapiens ]
• Official Symbol: RFXAP
• Synonyms: RFXAP; regulatory factor X-associated protein; RFX-associated protein; RFX DNA-binding complex 36 kDa subunit
• Gene ID: 5994
• mRNA Refseq: NM_000538
• Protein Refseq: NP_000529
• MIM: 601861
• UniProt ID: O00287
• Chromosome Location: 13q14
• Pathway: Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Primary immunodeficiency, organism-specific biosystem; Primary immunodeficiency, conserved biosystem; Tuberculosis, organism-specific biosystem; Tuberculosis, conserved biosystem
• Function: DNA binding; sequence-specific DNA binding transcription factor activity; transcription coactivator activity