Recombinant Human Regulator Of G-protein Signaling 16, His-tagged

• Cat.No.: RGS16-2031H
• Product Overview: Recombinant Human RGS16 protein with his tag was expressed inE.coliand purified by using conventional chromatography techniques, 24.9 kDa (222aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: RGS16, also known as regulator of G-protein signaling 16, belongs to "regulator of G protein signaling" family and negatively regulates G protein coupled receptor signalling. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP bound form. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade.
• Form: Liquid. In Phosphate Buffered Saline (pH7.4) containing 20% glycerol 0.1M NaCl.
• Purity: > 90% by SDS – PAGE.
• Concentration: 0.5 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MCRTLAAFPT TCLERAKEFK TRLGIFLHKS EL GCD TGSTG KFEWGSKHSK ENRNFSEDVL GWRESFDLLLSSKNGVAAFH AFLKT EFSEE NLEFWLACEE FKKIRSATKL ASRAHQIFEE FICSEAPKEV NIDHETRELT RMNLQTATAT CFDAAQGKTRTLMEKDSYPR FLKSPAYRDL AAQASAASAT LS SCSLDEPS HT.
• Storage: can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: RGS16 regulator of G-protein signaling 16 [ Homo sapiens ]
• Synonyms: regulator of G-protein signaling 16; RGS-R; A28-RGS14; A28-RGS14P; RGS16; hRGS-r; retinal-specific RGS; retinally abundant regulator of G-protein signaling; RGSR; RGS-r; Retinally abundant regulator of G-protein signaling
• Gene ID: 6004
• mRNA Refseq: NM_002928
• Protein Refseq: NP_002919
• MIM: 602514
• UniProt ID: O15492
• Chromosome Location: 1q25-q31
• Function: GTPase activator activity; calmodulin binding; signal transducer activity