Recombinant Human RECQL4, His-tagged

• Cat.No.: RECQL4-3747H
• Product Overview: ATP-dependent DNA helicase Q4 (RECQL4), partial

Specification

• Species: Human
• Source: E.Coli/Yeast
• Tag: His
• Protein Length: 1208
• Description: The protein encoded by this gene is a DNA helicase that belongs to the RecQ helicase family. DNA helicases unwind double-stranded DNA into single-stranded DNAs and may modulate chromosome segregation. This gene is predominantly expressed in thymus and testis. Mutations in this gene are associated with Rothmund-Thomson, RAPADILINO and Baller-Gerold syndromes.
• Form: This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
• Purity: >90%
• Notes: Small volumes of RECQL4 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
• Storage: Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
• Storage Buffer: PBS pH 7.4, 50% glycerol
• Warning: This product is for research use only. Not for use in diagnostic or therapeutic procedures.

Gene Information

• Gene Name: RECQL4 RecQ protein-like 4 [ Homo sapiens ]
• Official Symbol: RECQL4
• Synonyms: RECQL4; RecQ protein-like 4; ATP-dependent DNA helicase Q4; RecQ4; DNA helicase, RecQ-like type 4; DNA helicase, RecQ-like, type 4; RECQ4
• Gene ID: 9401
• mRNA Refseq: NM_004260
• Protein Refseq: NP_004251
• MIM: 603780
• UniProt ID: O94761
• Chromosome Location: 8q24.3
• Function: ATP binding; ATP-dependent 3-5 DNA helicase activity; ATP-dependent helicase activity; DNA strand annealing activity; bubble DNA binding; helicase activity; hydrolase activity; nucleic acid binding; nucleotide binding; zinc ion binding