Recombinant Human RBFOX2 protein, His-tagged

• Cat.No.: RBFOX2-211H
• Product Overview: Recombinant Human RBFOX2(aa 1-380) fused with His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-380 a.a.
• Description: RBFOX2 / RBM9 is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts.
• Form: 20 mM Tris, pH 8.0, 500 mM NaCl, 50% glycerol
• Molecular Mass: 44.4 kD
• AA Sequence: MEKKKMVTQG NQEPTTTPDA MVQPFTTIPF PPPPQNGIPTEYGVPHTQDY AGQTGEHNLT LYGSTQAHGE QSSNSPSTQNGSLTTEGGAQ TDGQQSQTQS SENSESKSTP KRLHVSNIPFRFRDPDLRQM FGQFGKILDV EIIFNERGSK GFGFVTFENSADADRAREKL HGTVVEGRKI EVNNATARVM TNKKMVTPYANGWKLSPVVG AVYGPELYAA SSFQADVSLG NDAAVPLSGRGGINTYIPLI SLPLVPGFPY PTAATTAAAF RGAHLRGRGRTVYGAVRAVP PTAIPAYPGV VYQDGFYGAD LYGGYAAYRYAQPATATAAT AAAAAAAAYS DGYGRVYTAD PYHALAPAASYGVGAVASLY RGGYSRFAPY
• Storage: Long term: -80 centigrade; Short term: -20 centigrade. Avoid freeze-thaw cycles.

Gene Information

• Gene Name: RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 [ Homo sapiens ]
• Official Symbol: RBFOX2
• Synonyms: RBFOX2; RNA binding protein, fox-1 homolog (C. elegans) 2; RBM9, RNA binding motif protein 9; RNA binding protein fox-1 homolog 2; FOX 2; hexaribonucleotide binding protein 2; HNRBP2; HRNBP2; fox-1 homolog B; fox-1 homologue; RNA-binding motif protein 9; hexaribonucleotide-binding protein 2; repressor of tamoxifen transcriptional activity; RTA; fxh; FOX2; RBM9; Fox-2; dJ106I20.3
• Gene ID: 23543
• mRNA Refseq: NM_014309
• Protein Refseq: NP_055124
• MIM: 612149
• UniProt ID: O43251
• Chromosome Location: 22q12-q13
• Function: RNA binding; nucleotide binding; protein binding; transcription corepressor activity; transcription factor binding