Recombinant Human RASGRF2 Protein, MYC/DDK-tagged

• Cat.No.: RASGRF2-495H
• Product Overview: Recombinant human RASGRF2 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: Myc&DDK
• Description: RAS GTPases cycle between an inactive GDP-bound state and an active GTP-bound state. This gene encodes a calcium-regulated nucleotide exchange factor activating both RAS and RAS-related protein, RAC1, through the exchange of bound GDP for GTP, thereby, coordinating the signaling of distinct mitogen-activated protein kinase pathways. [provided by RefSeq, Oct 2011].
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 140.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: Ras protein specific guanine nucleotide releasing factor 2[ Homo sapiens ]
• Official Symbol: RASGRF2
• Synonyms: GRF2; RAS-GRF2
• Gene ID: 5924
• mRNA Refseq: NM_006909.2
• Protein Refseq: NP_008840.1
• MIM: 606614
• UniProt ID: O14827