Recombinant Human RASAL1 cell lysate

• Cat.No.: RASAL1-1475HCL

Specification

• Species: Human
• Tag: Non
• Description: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues.
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: RASAL1 RAS protein activator like 1 (GAP1 like) [ Homo sapiens ]
• Official Symbol: RASAL1
• Synonyms: RASAL1; RAS protein activator like 1 (GAP1 like); rasGAP-activating-like protein 1; RASAL; GAP1 like protein
• Gene ID: 8437
• mRNA Refseq: NM_001193520
• Protein Refseq: NP_001180449
• MIM: 604118
• UniProt ID: O95294
• Chromosome Location: 12q23-q24
• Function: Ras GTPase activator activity; metal ion binding; phospholipid binding